Metabolism of the joints and cartilage
Normal cartilage functions are determined by the constant alternation between an increase and decrease in pressure inside the joint. Although the cartilage has no nerves, blood vessels or lymphatic vessels, this changing pressure triggers a suction action that allows nutrients to enter the cartilage and metabolic waste to be removed.
The cartilage metabolism is influenced by many factors:
- Well-functioning regulatory mechanisms: a number of substances are thought to be involved in regulating the cartilage metabolism, including cytokines, growth factors, collagen fragments, vitamins and minerals.
- Physical activity can also have different effects on the cartilage metabolism. An excessive workload or constant stress can contribute to unwanted changes. On the other hand, if the joint is immobile or the load on the joint is significantly reduced, this reduces the activity of the chondrocytes, which leads to less intracellular material being released. To maintain healthy cartilage in the joints, it is important to maintain an optimal balance of exercise, which does not overload the joints, but also does not let them get “lazy”, so that the breakdown of cartilaginous tissue does not outpace the synthesis.
- It is important for all cartilage components to have access to sufficient molecules for synthesis and a proper uptake. This requires adequate nutrition, to ensure that the joint cartilage synthesis is not lacking in any substances.
